The advantages of isobutane canister stove fuel makes it extremely popular in the backcountry: clean burning, no spills, and ease of use. The major drawbacks of canister fuel revolve around the inability to transfer fuel between canisters, resulting in partially used canisters piling up, and forcing us to carry multiple partially used canisters to avoid wasting fuel. On top of that, we often end up paying more per unit of fuel, as the cost is disproportionally higher in smaller canisters.
Source: Alleviate the Disadvantages of Fuel Canisters with this Simple Device | Gear Institute